Hydrogen sulphide has therapeutic functions but because it is a gas its delivery as a drug poses specific difficulties. Porous materials have been emerging as serious candidates for the storage and release of small gas molecules with therapeutic effects. In this work, we study microporous (A, and Y zeolites; ETS-4 and ETS-10 titanosilicates) and mesoporous (SBA-15 with and without surface amines functionalization) materials.

The experimental determination of the H₂S amounts released from the porous materials in liquid phase was challenging. For this, two methodologies were used, the detection through the methylene blue reaction and by a selective electrode. In the end, considering the storage amounts, the release profile and the cytotoxicity, 4A zeolite and ETS-10 titanosilicate showed the best properties.

硫化氢具有治疗功能，但由于它是气体，因此作为药物的输送会带来特殊的困难。多孔材料已经成为用于存储和释放具有治疗作用的小气体分子的重要候选材料。在这项工作中，我们研究了微孔（A和Y沸石； ETS-4和ETS-10钛硅酸盐）和中孔（具有和不具有表面胺功能化的SBA-15）材料。

从多孔材料在液相中释放出的H ₂ S量的实验测定具有挑战性。为此，使用了两种方法，即通过亚甲蓝反应和通过选择性电极进行检测。最后，考虑到储存量，释放特性和细胞毒性，4A沸石和ETS-10钛硅酸盐显示出最佳性能。