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Zeolitic Imidazolate Framework-90 Nanoparticles as Nanozymes to Mimic Organophosphorus Hydrolase
ACS Applied Nano Materials ( IF 5.3 ) Pub Date : 2021-04-13 , DOI: 10.1021/acsanm.1c00540
Tong Fu 1 , Chengjie Xu 1 , Rongrong Guo 1 , Changxu Lin 1 , Yanyan Huang 2 , Yonghua Tang 1 , Hao Wang 1 , Qifan Zhou 1 , Youhui Lin 1
Affiliation  

Nanozymes are catalytically active nanomaterials that can mimic the catalytic properties of natural enzymes. However, little research has focused on nanozymes for mimicking organophosphate hydrolase (OPH) activity. Herein, we report that the zeolitic imidazolate framework-90 (ZIF-90) nanoparticles synthesized by the self-assembly of imidazole and metal ions have an average size of about 800 nm. They can serve as a new nanozyme to mimic OPH, which can effectively hydrolyze organophosphorus methyl parathion. More importantly, the as-prepared ZIF-90 nanozyme shows higher stability and superior recyclability. Our work will bring new possibilities for design and development of other novel nanozymes based on metal–organic framework materials.

中文翻译:

沸石咪唑盐骨架-90纳米颗粒作为模拟有机磷水解酶的纳米酶。

纳米酶是具有催化活性的纳米材料,可以模拟天然酶的催化特性。但是,很少有研究集中在模拟有机磷酸水解酶(OPH)活性的纳米酶上。在本文中,我们报道了通过咪唑和金属离子的自组装合成的沸石咪唑酸盐骨架-90(ZIF-90)纳米粒子的平均大小约为800 nm。它们可以用作模仿OPH的新型纳米酶,可以有效地水解有机磷甲基对硫磷。更重要的是,所制备的ZIF-90纳米酶显示出更高的稳定性和优异的可回收性。我们的工作将为基于金属-有机骨架材料的其他新型纳米酶的设计和开发带来新的可能性。
更新日期:2021-04-23
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