富含藻毒素的海喷雾气溶胶：方法，机理和人体暴露,Environmental Science & Technology

当前位置： X-MOL 学术 › Environ. Sci. Technol. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

富含藻毒素的海喷雾气溶胶：方法，机理和人体暴露
Environmental Science & Technology ( IF 10.8 ) Pub Date : 2021-04-12 , DOI: 10.1021/acs.est.1c00995
Emmanuel Van Acker ₁ , Steve Huysman ₂ , Maarten De Rijcke ₃ , Jana Asselman _{1,

4} , Karel A. C. De Schamphelaere ₁ , Lynn Vanhaecke _{2,

5} , Colin R. Janssen _{1,

4}

Affiliation

迄今为止，很少有研究检查过海喷雾气溶胶（SSA）在人类暴露于有害和有益海洋化合物中的作用。据报道，两组藻毒素（短毒素和卵毒素）会在有害藻华期间诱发呼吸综合征。但是，从未检查过其他常见海洋藻毒素的雾化作用和沿海空气中的浓度。这项研究提供了第一个（实验）证据和冈田酸（OA），同型毒素和dinophysistoxin-1的雾化使用海水加有毒藻类并在海洋气溶胶参考罐（MART）中实际生产SSA的雾化特性。这些藻毒素的雾化潜力是相对于地下水而言，它们在SSA中的富集程度达到了78到1769倍。为了获得并支持这些结果，R ² > 0.99），回收率（85.3–101.8％）和精度（RSD≤17.2％）。我们还通过原位SSA采样和同时在MART中使用天然海水进行的雾化实验研究了天然植物毒素的空气浓度。这种方法使我们能够间接地量化比利时沿海空气中OA浓度（0.6-51 pg m ^-3）的（无害）幅度。总体而言，这项研究为丰富的海洋化合物雾化提供了新的见识，并提出了评估其空中传播及其对人体健康影响的框架。

"点击查看英文标题和摘要"

Phycotoxin-Enriched Sea Spray Aerosols: Methods, Mechanisms, and Human Exposure

To date, few studies have examined the role of sea spray aerosols (SSAs) in human exposure to harmful and beneficial marine compounds. Two groups of phycotoxins (brevetoxins and ovatoxins) have been reported to induce respiratory syndromes during harmful algal blooms. The aerosolization and coastal air concentrations of other common marine phycotoxins have, however, never been examined. This study provides the first (experimental) evidence and characterization of the aerosolization of okadaic acid (OA), homoyessotoxin, and dinophysistoxin-1 using seawater spiked with toxic algae combined with the realistic SSA production in a marine aerosol reference tank (MART). The potential for aerosolization of these phycotoxins was highlighted by their 78- to 1769-fold enrichment in SSAs relative to the subsurface water. To obtain and support these results, we first developed an analytical method for the determination of phycotoxin concentrations in SSAs, which showed good linearity (R² > 0.99), recovery (85.3–101.8%), and precision (RSDs ≤ 17.2%). We also investigated natural phycotoxin air concentrations by means of in situ SSA sampling with concurrent aerosolization experiments using natural seawater in the MART. This approach allowed us to indirectly quantify the (harmless) magnitude of OA concentrations (0.6–51 pg m^–3) in Belgium’s coastal air. Overall, this study provides new insights into the enriched aerosolization of marine compounds and proposes a framework to assess their airborne exposure and effects on human health.

更新日期：2021-05-04

点击分享查看原文

点击收藏

阅读更多本刊新发论文本刊介绍/投稿指南