Synthesis and biological activity of novel Pyrazolo[3,4-d]pyrimidin-4-one derivatives as potent antifungal agent,Pest Management Science

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Synthesis and biological activity of novel Pyrazolo[3,4-d]pyrimidin-4-one derivatives as potent antifungal agent
Pest Management Science ( IF 3.8 ) Pub Date : 2021-04-09 , DOI: 10.1002/ps.6406
Wei Wang _{1,

2} , Xiang Cheng ₁ , Xue Cui ₃ , Dongguo Xia ₁ , Ziqing Wang ₁ , Xianhai Lv ₁

Affiliation

To promote the discovery and development of new fungicide with novel scaffolds or modes of action, a series of novel 5-(2-chloroethyl)-1-phenyl-6-(pyridin-4-yl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one derivatives were synthesized, and evaluated for their antifungal activities.

中文翻译：

新型 Pyrazolo[3,4-d]pyrimidin-4-one 衍生物作为有效抗真菌剂的合成和生物活性

为促进具有新型支架或作用方式的新型杀菌剂的发现和开发，一系列新型5-(2-氯乙基)-1-苯基-6-(吡啶-4-基)-1,5-二氢-4H合成了 -pyrazolo[3,4-d]pyrimidin-4-one 衍生物，并评估了它们的抗真菌活性。

更新日期：2021-06-10

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