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Calculating the divergence time by direct comparison between individuals and the out-group
bioRxiv - Evolutionary Biology Pub Date : 2021-04-24 , DOI: 10.1101/2021.04.04.438302
Tingting Sun , Qing Liu , Meiqi Shang , Kejian Wang

Investigating the divergence time between different populations has been of fundamental interest in evolution biology. In this study, we reanalysed the mitochondrial and Y chromosome DNA of the 1000 Genomes Project, and revealed that most single nucleotide polymorphisms (SNPs) are specific to minority and would be classified as low-frequency mutations. Using these polymorphisms, we recalculated the divergence time of different populations by direct comparison between individuals and the out-group.

中文翻译:

通过直接比较个体和外部群体来计算发散时间

研究不同种群之间的差异时间是进化生物学的基本兴趣所在。在这项研究中,我们重新分析了1000个基因组计划的线粒体和Y染色体DNA,并揭示了大多数单核苷酸多态性(SNP)是少数族裔所特有的,将被归类为低频突变。使用这些多态性,我们通过直接比较个体与外部群体之间的差异,重新计算了不同人群的发散时间。
更新日期:2021-04-24
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