Current Opinion in Colloid & Interface Science ( IF 7.9 ) Pub Date : 2021-03-31 , DOI: 10.1016/j.cocis.2021.101454 Rachael A Day 1 , Ellen M Sletten 1
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Photodynamic therapy (PDT) is a treatment modality in which a photosensitizer is irradiated with light, producing reactive oxygen species, often via energy transfer with oxygen. As it is common for tumors to be hypoxic, methods to deliver photosensitizer and oxygen are desirable. One such approach is the use of perfluorocarbons, molecules in which all C–H bonds are replaced with C–F bonds, to co-deliver oxygen because of the high solubility of gases in perfluorocarbons. This review highlights the benefits and limitations of several fluorinated nanomaterial architectures for use in PDT.
中文翻译：
用于光动力治疗的全氟化碳纳米材料
光动力疗法 (PDT) 是一种治疗方式，其中光敏剂受到光照射，通常通过与氧气的能量转移产生活性氧。由于肿瘤缺氧是很常见的，因此需要提供光敏剂和氧气的方法。其中一种方法是使用全氟化碳（其中所有 C-H 键都被 C-F 键取代的分子）来共同传递氧气，因为气体在全氟化碳中的溶解度很高。本综述强调了用于 PDT 的几种氟化纳米材料结构的优点和局限性。
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