A novel water-soluble conjugated macrocyclic tetramaleimide (WCMT-1) with far red/near-infrared (FR/NIR) fluorescence emission has been rationally designed and successfully synthesized. WCMT-1 with the twisted donor (D) and acceptor (A) structures make it possess both aggregation-induce emission (AIE) and twist intramolecular charge transfer (TICT) characteristics. Due to the AIE effects, WCMT-1 exhibits a strong fluorescence in non-polar solvents (the quantum yield of WCMT-1 reaches to 33.7% in toluene and 32.5% in CCl₄), but it is quenched in an aqueous solution caused by the TICT process. However, by the introduction of sodium lauryl sulfonate (SLS) into the WCMT-1 aqueous solution, the in situ generated WCMT-1&SLS supra-amphiphile resulted in remarkable recovery of FR/NIR fluorescence. Furthermore, combined with its large Stokes shift and good water solubility, the bioimaging experiments towards HeLa and HepG2 cells have also been conducted to give a good performance.

合理设计并成功合成了新型的具有远红/近红外（FR / NIR）荧光发射的水溶性共轭大环四马来酰亚胺（WCMT-1）。WCMT-1具有扭曲的供体（D）和受体（A）结构，使其兼具聚集诱导发射（AIE）和扭曲的分子内电荷转移（TICT）特性。由于AIE的作用，WCMT-1在非极性溶剂中表现出很强的荧光性（在甲苯中WCMT-1的量子产率达到33.7％，在CCl _4中达到32.5％的量子产率）。），但在TICT工艺导致的水溶液中淬灭。但是，通过将月桂基磺酸钠（SLS）引入WCMT-1水溶液中，原位生成的WCMT-1＆SLS超两亲物导致了FR / NIR荧光的显着恢复。此外，结合其较大的斯托克斯位移和良好的水溶性，还对HeLa和HepG2细胞进行了生物成像实验，以提供良好的性能。