A NIR fluorescent probe (DDAA) derived from fluorophore DDAO with alanine as the recognition group was developed for sensing aminopeptidase N (APN) in gut microbiota. Using DDAA as the real-time guidance tool for the fluorescence imaging of intestinal microorganism, target bacteria and saccharomycete possessing active APN were identified successfully from human feces.

中文翻译：

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使用可激活的NIR荧光探针实时鉴定具有氨肽酶N的肠道菌群

开发了一种以丙氨酸为识别基团的荧光团DDAO衍生的NIR荧光探针（DDAA），用于检测肠道菌群中的氨肽酶N（APN）。使用DDAA作为肠道微生物荧光成像的实时指导工具，从人粪便中成功鉴定出具有活性APN的靶细菌和酿酒菌。