The coronavirus continues to take a devastating toll on the population of the USA. But that toll is not identical across all segments of the population. Specifically, Black citizens are more likely than their White counterparts to experience the dislocations associated with the coronavirus. Nor is the extent of racial differences fully known, given limitations to the testing, hospitalization, and other data currently compiled. What does emerge, however, is an understanding that the reported outcomes reflect social inequities rather than biological predispositions. The inequities flow from both historical forces and contemporary ones that leave sizeable fractions of the Black population without access to quality healthcare or safe environments. The discrepancies suggest that the development of safe and effective vaccines might not eliminate the racial disparities associated with COVID-19, for that development will not alone erode levels of structural racism in the society. Concerted actions that engage multiple segments and participants are demanded.