Abstract A novel synthesis of 2,3-dihydroimidazo[1,2-a]pyridin-5(1H)-one 4 and its derivatives were described. Preliminary bioassays showed that some of the target compounds exhibited excellent insecticidal activities against brown planthopper (Nilaparvata lugens), cowpea aphids (Aphis craccivora) (4, 5a, 5c, 5g, 5h, 5j, 5r, 6b, 6e) and carmine spider mite (Tetranychus cinnabarinus (5f, 5s, 6a) at 500 mg/L. Among them, compound 4 was still active against brown planthopper and cowpea aphids at 4 mg/L. The insecticidal activities were influenced by the types and position of the substituents, which provided guidance for the structure modifications.

中文翻译：

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2,3-二氢咪唑并[1,2-a]吡啶-5（1H）-一衍生物的合成及杀虫生物活性

摘要描述了一种新的2,3-二氢咪唑并[1,2-a]吡啶-5（1H）-one 4及其衍生物的合成方法。初步生物测定表明，某些目标化合物对褐飞虱（Nilaparvata lugens），cow豆蚜虫（Aphis craccivora）（4、5a，5c，5g，5h，5j，5r，6b，6e）和胭脂红蜘蛛具有极佳的杀虫活性。 （朱砂叶螨（Tetranychus cinnabarinus（5f，5s，6a）在500 mg / L。其中，化合物4在4 mg / L时仍对褐飞虱和cow豆蚜有活性）。杀虫活性受取代基的类型和位置的影响，为结构修改提供了指导。