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Synthesis and antiviral activity of 4-(7,7-dimethyl-4-[4-{N-aroyl/benzyl}1-piperazinyl]-5,6,7,8-tetrahydroquinazolin-2-yl)morpholine derivatives
ARKIVOC Pub Date : 2017-06-25 , DOI: 10.24820/ark.5550190.p010.037
Balaraman Selvakumar , S.P. Vaidyanathan , Madhuri Subbiah , Kuppanagounder P. Elango

The synthesis of a series of 4-(7,7-dimethyl-4-[4-{N-aroyl/(het)aroyl/ benzyl}1-piperazinyl]-5,6,7,8tetrahydroquinazolin-2-yl)morpholine derivatives has been described. The antiviral activity of these compounds against avian paramyxovirus (APMV-1), which is a Newcastle disease virus has also been screened.

中文翻译:

4-(7,7-二甲基-4-[4-{N-芳酰基/苄基}1-哌嗪基]-5,6,7,8-四氢喹唑啉-2-基)吗啉衍生物的合成及抗病毒活性

一系列4-(7,7-二甲基-4-[4-{N-芳酰基/(杂)芳酰基/苄基}1-哌嗪基]-5,6,7,8四氢喹唑啉-2-基)吗啉的合成已经描述了衍生物。还筛选了这些化合物对禽副粘病毒 (APMV-1)(一种新城疫病毒)的抗病毒活性。
更新日期:2017-06-25
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