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Ni2P Nanosheets: A High Catalytic Activity Platform for Electrochemical Detection of Acetaminophen
Chinese Journal of Chemistry ( IF 5.5 ) Pub Date : 2021-03-13 , DOI: 10.1002/cjoc.202100043 Ming Wei 1, 2 , Wenbo Lu 1 , Guoqin Liu 1 , Yimin Jiang 1 , Xuebo Liu 1 , Liwei Bai 1 , Xiaowei Cao 3 , Jianfeng Jia 1 , Haishun Wu 1
Chinese Journal of Chemistry ( IF 5.5 ) Pub Date : 2021-03-13 , DOI: 10.1002/cjoc.202100043 Ming Wei 1, 2 , Wenbo Lu 1 , Guoqin Liu 1 , Yimin Jiang 1 , Xuebo Liu 1 , Liwei Bai 1 , Xiaowei Cao 3 , Jianfeng Jia 1 , Haishun Wu 1
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Accurate determination of acetaminophen concentration is essential for studying the metabolic status of acetaminophen in clinical practice. In this study, nickel phosphide was used for electrochemical detection of acetaminophen for the first time. An electrochemical acetaminophen sensor based on Ni2P nanosheets was successfully constructed and the sensor showed many convincing properties: (a) a good linear range (0.5 μmol/L—4.5 mmol/L); (b) a moderate sensitivity (131.1 μA·mmol–1·L·cm–2); (c) a low detection limit (0.107 μmol/L). In addition, the sensor also showed excellent selectivity, robust stability and reliable repeatability. Further experiments demonstrate that the prepared sensor can be used for quantitative detection of acetaminophen in commercial medical drugs.
中文翻译：
Ni2P 纳米片：用于对乙酰氨基酚电化学检测的高催化活性平台
对乙酰氨基酚浓度的准确测定对于在临床实践中研究对乙酰氨基酚的代谢状态至关重要。本研究首次将磷化镍用于对乙酰氨基酚的电化学检测。成功构建了基于Ni 2 P纳米片的电化学对乙酰氨基酚传感器，该传感器表现出许多令人信服的特性：（a）良好的线性范围（0.5 μmol/L—4.5 mmol/L）；(b) 中等灵敏度（131.1 μA·mmol –1 ·L·cm –2); (c) 低检测限 (0.107 μmol/L)。此外，该传感器还表现出出色的选择性、强大的稳定性和可靠的重复性。进一步的实验表明，所制备的传感器可用于商业医疗药物中对乙酰氨基酚的定量检测。
更新日期：2021-03-13
中文翻译：
Ni2P 纳米片：用于对乙酰氨基酚电化学检测的高催化活性平台
对乙酰氨基酚浓度的准确测定对于在临床实践中研究对乙酰氨基酚的代谢状态至关重要。本研究首次将磷化镍用于对乙酰氨基酚的电化学检测。成功构建了基于Ni 2 P纳米片的电化学对乙酰氨基酚传感器，该传感器表现出许多令人信服的特性：（a）良好的线性范围（0.5 μmol/L—4.5 mmol/L）；(b) 中等灵敏度（131.1 μA·mmol –1 ·L·cm –2); (c) 低检测限 (0.107 μmol/L)。此外，该传感器还表现出出色的选择性、强大的稳定性和可靠的重复性。进一步的实验表明，所制备的传感器可用于商业医疗药物中对乙酰氨基酚的定量检测。
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