当前位置: X-MOL 学术 › Journal of the Serbian Chemical Society › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Benzylation of N-phenyl-2-phenylacetamide under microwave irradiation
Journal of the Serbian Chemical Society Pub Date : 2008-01-01 , DOI: 10.2298/jsc0810945m
Dusan Mijin 1 , Masa Prascevic 1 , Slobodan Petrovic 2
Affiliation  

N-Phenyl-2-phenylacetamide was alkylated with benzyl chloride in the presence of powdered potassium hydroxide under microwave irradiation in a solvent-free system. The reactions were also performed in the presence of phase-transfer catalysts. The formation of N-, O- and C-products of alkylation was followed by gas chromatography. The N-product was found to be the main product under microwave irradiation. The O-product was obtained in higher yields when an excess of base and benzyl chloride was used.

中文翻译:

微波辐射下N-苯基-2-苯基乙酰胺的苯甲酰化

在无溶剂体系中在微波辐射下,在粉末状氢氧化钾存在下,用苄基氯烷基化N-苯基-2-苯基乙酰胺。该反应也在相转移催化剂的存在下进行。气相色谱法随后形成烷基化的N-,O-和C-产物。发现N产物是微波辐射下的主要产物。当使用过量的碱和苄基氯时,以更高的产率获得O产物。
更新日期:2008-01-01
down
wechat
bug