The title compound was prepared by an aza-Michael addition reaction between 1-[1-(4-chlorobenzenesulfonyl)-1H-indole-3-yl]prop-2-en-1-one and 2-piridylpiperazine catalyzed by SiO2. The structural identity of the title compound was proven by elemental analysis and spectroscopic methods (IR, NMR). The compound was assayed in a binding assay at the 5-HT6 receptor, showing poor affinity.

中文翻译：

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1- [1-（4-氯苯磺酰基）-1H-吲哚-3-基] -3- [4-（吡啶-2-基）哌嗪-1-基]丙-1-酮

通过在SiO 2催化下的1- [1-（4-氯苯磺酰基）-1H-吲哚-3-基]丙-2-烯-1-酮与2-吡啶基哌嗪之间的氮杂-迈克尔加成反应制备标题化合物。通过元素分析和光谱法（IR，NMR）证明了标题化合物的结构相同性。在结合测定中在5-HT 6受体处测定了该化合物，显示出较弱的亲和力。