Recent Advances in Nanopore Sensing†,Chinese Journal of Chemistry

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Recent Advances in Nanopore Sensing†
Chinese Journal of Chemistry ( IF 5.5 ) Pub Date : 2021-02-25 , DOI: 10.1002/cjoc.202000721
Mengjie Cui ₁ , Yaxian Ge ₁ , Xiao Zhuge ₁ , Xin Zhou ₁ , Dongmei Xi ₁ , Shusheng Zhang ₁

Affiliation

Nanopore sensing is developing into a powerful label-free approach to investigate the features of biomolecules at the single-molecule level. When a charged molecule is captured within a nanopore, it modulates the ionic current, which can be recorded in real time to reveal the properties of the target molecule. To date, nanopores have been used to sense a variety of analytes, including DNA, RNA, proteins, enzymes, small molecules, cancer cells, and metal ions, and can also provide information on biomolecular structures. In this review, we highlight the progress made in nanopore sensing over the past five years (2016—2020), and provide an outlook on future developments and directions in the field

中文翻译：

纳米孔传感的最新进展†

纳米孔传感正在发展成为一种强大的无标记方法，可以在单分子水平上研究生物分子的特征。当带电分子被捕获在纳米孔内时，它会调节离子电流，可以实时记录离子电流以揭示目标分子的特性。迄今为止，纳米孔已被用于检测多种分析物，包括 DNA、RNA、蛋白质、酶、小分子、癌细胞和金属离子，还可以提供有关生物分子结构的信息。在这篇综述中，我们重点介绍了纳米孔传感在过去五年（2016-2020）中取得的进展，并对该领域的未来发展和方向进行了展望

更新日期：2021-02-25

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