Nanogels based Polyethylene glycol diacrylate (PEGDA) attracted much attention due to their promising application in drug delivery and tissue engineering. Here, PEGDA photopolymerization at 532 nm with different initiating systems was investigated. Nanogels can be obtained using single 2′,4′,5′,7′-tetrabromofluorescein disodium salt (EY) as the photoinitiator. To increase the polymerization rate, EY, triethanolamine (TEOA), and diphenyl iodonium hexafluorophosphate (DPI) were investigated as a three-component initiating system. With that initiating system, the conversion of PEGDA double bond was higher than 90 % in 1 min at extremely low irradiation energy density (P= 0.95 mW/cm²). However, the conversion of PEGDA double bond was only 51.5 % in 1 min at the same irradiation energy density when using EY and TEOA as two-component initiating system. Subsequently, the corresponding mechanism of the three-component (EY-TEOA-DPI) initiating system was illustrated. DPI might participate in two ways of photooxidation and reduction, which dramatically improved the polymerization rate. The EY-TEOA-DPI initiating system is promising to be applied in the preparation of multifunctional hydrogels.

基于纳米凝胶的聚乙二醇二丙烯酸酯（PEGDA）由于在药物递送和组织工程中的应用前景广阔而备受关注。在这里，研究了PEGDA在532 nm下用不同的引发体系光聚合。纳米凝胶可以使用单个2'，4'，5'，7'-四溴荧光素二钠盐（EY）作为光引发剂来获得。为了提高聚合速率，研究了EY，三乙醇胺（TEOA）和六氟磷酸二苯基碘鎓（DPI）作为三组分引发体系。使用该引发系统，在极低的辐射能量密度（P = 0.95 mW / cm ^2）下，PEGDA双键的转化率在1分钟内高于90％。）。然而，当使用EY和TEOA作为两组分引发体系时，在相同的辐射能量密度下，PEGDA双键在1分钟内的转化率仅为51.5％。随后，说明了三组分（EY-TEOA-DPI）引发系统的相应机制。DPI可能参与光氧化和还原的两种方式，从而大大提高了聚合速率。EY-TEOA-DPI引发体系有望在多功能水凝胶的制备中得到应用。