Herein, we report the sulfonamide-functionalized covalent organic framework (COF-SO₃H) prepared from melamine and terephthalaldehyde and subsequent sulfonation, as an acidic porous catalyst for the one-pot preparation of polyhydroquinoline and 1,4-dihydropyridine derivatives. COF-SO₃H was characterized by FT-IR, EDX, TGA, SEM, XRD, and BET. This methodology offers several advantages including high yield, short reaction time, simple workup procedure, solvent-free conditions, ease of separation, and recyclability.

Graphic abstract

One-pot preparation of polyhydroquinoline and 1, 4-dihydropyridine derivatives

中文翻译：

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磺酰胺官能化的共价有机骨架（COF-SO 3 H）：一种高效的多相酸性催化剂，用于一锅制备聚氢喹啉和1,4-二氢吡啶衍生物

本文中，我们报道了由三聚氰胺和对苯二甲醛和随后的磺化反应制备的磺酰胺官能化共价有机骨架（COF-SO ₃ H），该酸性骨架催化剂是一锅制备聚氢喹啉和1,4-二氢吡啶衍生物的酸性多孔催化剂。通过FT-IR，EDX，TGA，SEM，XRD和BET对COF-SO ₃ H进行了表征。该方法具有许多优点，包括高收率，较短的反应时间，简单的后处理程序，无溶剂条件，易于分离和可回收性。

图形摘要

一锅法制备多氢喹啉和1,4-二氢吡啶衍生物