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Clinical Outcomes after Mitral Valve Repair with the Physio II Annuloplasty Ring
The Thoracic and Cardiovascular Surgeon ( IF 1.3 ) Pub Date : 2021-02-18 , DOI: 10.1055/s-0040-1722651
Thilo Noack 1 , Franz Sieg 1 , Mateo Marin Cuartas 1 , Ricardo Spampinato 1 , David Holzhey 1 , Joerg Seeburger 1 , Michael Andrew Borger 1
Affiliation  

Background Mitral valve (MV) repair with annuloplasty is the standard of care in patients with primary degenerative mitral regurgitation (DMR). Newer generations of annuloplasty rings have been developed with the goals of closer reproduction of native annular geometry and easier implantation. This study investigates the short-term and 5-year clinical outcomes of MV repair with the Carpentier-Edwards (CE) Physio II annuloplasty ring.

Methods This is an observational study including a total of 486 patients who underwent MV repair for DMR using the CE Physio II annuloplasty ring between 2011 and 2016.

Results Mean age was 54.8 ± 12.1 years, 364 patients (74.9%) were males, and 84 patients (17.3%) presented with atrial fibrillation. Mean left ventricular ejection fraction was 62.3 ± 7.3%. Mean logistic EuroSCORE was 2.7 ± 2.4%. New York Heart Association functional class III–IV symptoms were present in 134 (27.6%) patients preoperatively. Isolated MV repair was performed via a right-sided mini-thoracotomy in 479 patients (98.6%). Concomitant procedures included ablation for atrial fibrillation in 83 patients (17.1%) and closure of atrial septum defect in 88 patients (18.1%). Median size of implanted annuloplasty rings was 34 mm (interquartile range: 34–38 mm). Mean cardiopulmonary bypass time was 116 ± 34 minutes and mean cross-clamp time was 74 ± 25 minutes. Thirty-day mortality was 0.4%. The Kaplan–Meier 4-year survival was 98.5%. Freedom from MV reoperation was 96.2 and 94.0% at 1 and 4 years.

Conclusion MV repair with the CE Physio II annuloplasty ring is associated with excellent midterm clinical outcome.



中文翻译:

使用 Physio II 瓣环成形术环修复二尖瓣后的临床结果

背景 二尖瓣 (MV) 修复与瓣环成形术是原发性退行性二尖瓣关闭不全 (DMR) 患者的护理标准。新一代的瓣环成形术环已被开发出来,目标是更接近地再现原生环状几何形状和更容易植入。本研究调查使用 Carpentier-Edwards (CE) Physio II 瓣环成形术环修复 MV 的短期和 5 年临床结果。

方法 这是一项观察性研究,包括 2011 年至 2016 年期间使用 CE Physio II 瓣环成形术环接受 MV 修复 DMR 的总共 486 名患者。

结果 平均年龄为 54.8 ± 12.1 岁,364 名患者(74.9%)为男性,84 名患者(17.3%)出现房颤。平均左心室射血分数为 62.3 ± 7.3%。平均逻辑 EuroSCORE 为 2.7 ± 2.4%。134 名 (27.6%) 患者术前出现纽约心脏协会功能等级 III-IV 症状。479 名患者(98.6%)通过右侧小切口进行了孤立的 MV 修复。伴随手术包括 83 名患者 (17.1%) 的房颤消融和 88 名患者 (18.1%) 的房间隔缺损闭合术。植入的瓣环成形术环的中位尺寸为 34 毫米(四分位距:34-38 毫米)。平均体外循环时间为 116 ± 34 分钟,平均交叉钳夹时间为 74 ± 25 分钟。30 天死亡率为 0.4%。Kaplan-Meier 4 年生存率为 98.5%。

结论 CE Physio II 瓣环成形术环的 MV 修复与良好的中期临床结果相关。

更新日期:2021-02-19
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