<br>E-PSMA：PSMA-PET 的 EANM 标准化报告指南 v1.0,European Journal of Nuclear Medicine and Molecular Imaging

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E-PSMA：PSMA-PET 的 EANM 标准化报告指南 v1.0
European Journal of Nuclear Medicine and Molecular Imaging ( IF 8.6 ) Pub Date : 2021-02-19 , DOI: 10.1007/s00259-021-05245-y
Francesco Ceci ₁ , Daniela E Oprea-Lager ₂ , Louise Emmett _{3,

4} , Judit A Adam ₅ , Jamshed Bomanji ₆ , Johannes Czernin ₇ , Matthias Eiber ₈ , Uwe Haberkorn ₉ , Michael S Hofman _{10,

11} , Thomas A Hope ₁₂ , Rakesh Kumar ₁₃ , Steven P Rowe ₁₄ , Sarah M Schwarzenboeck ₁₅ , Stefano Fanti ₁₆ , Ken Herrmann ₁₇

Affiliation

Nuclear Medicine, Department of Medical Sciences, University of Turin, Turin, Italy.
Department of Radiology & Nuclear Medicine, Amsterdam University Medical Centers, VU University Medical Center, Cancer Center Amsterdam, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands.
St. Vincent's Clinical School, University of New South Wales, Kensington, NSW, Australia.
Department of Theranostics and Nuclear Medicine, St. Vincent's Hospital Sydney, Darlinghurst, NSW, Australia.
Department of Radiology & Nuclear Medicine, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands.
Department of Nuclear Medicine, University College London Hospitals NHS Foundation Trust, London, UK.
Ahmanson Translational Theranostics Division, Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, 90095, USA.
School of Medicine, Department of Nuclear Medicine, Technische Universität München, Munich, Germany.
Department of Nuclear Medicine, Heidelberg University Hospital, Heidelberg, Germany.
Molecular Imaging and Therapeutic Nuclear Medicine, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.
Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, VIC, Australia.
Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA, USA.
Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, India.
Division of Nuclear Medicine, The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Department of Nuclear Medicine, Rostock University Medical Centre, Rostock, Germany.
Nuclear Medicine, IRCCS Azienda Ospedaliero-Universitaria di Bologna, University of Bologna, Bologna, Italy.
Department of Nuclear Medicine, University of Duisburg-Essen and German Cancer Consortium (DKTK), University Hospital Essen, Essen, Germany.

基本原理

需要制定前列腺特异性膜抗原 (PSMA)-正电子发射断层扫描 (PET) 解释的共识指南，以便在临床实践中提供更一致的报告。 PSMA-PET 解释的标准化也可能有助于提高临床试验中数据的可重复性。最后，需要 PSMA-PET 解释指南来向转诊医生传达结果的确切位置，以支持临床医生的治疗管理决策。

方法

成立了一个由 PSMA-PET 领域的全球专家组成的小组。小组成员的选择基于他们在 PCa 诊断或治疗方面的专业知识和发表记录、他们参与临床指南的情况以及他们在放射性标记 PSMA 抑制剂临床应用方面的专业知识。小组成员积极参与了修改后的非匿名德尔菲共识流程的所有阶段。

结果

根据修改后的德尔菲共识流程获得的结果，小组成员的建议已在 PSMA-PET 的结构化报告中得到实施。

结论

E-PSMA 标准化报告指南是由欧洲核医学协会 (EANM) 支持的文件，提供了 PSMA-PET 成像专家小组之间的共识声明，以开发前列腺癌中 PSMA-PET 的结构化报告，并统一诊断解释标准。

"点击查看英文标题和摘要"

E-PSMA: the EANM standardized reporting guidelines v1.0 for PSMA-PET

Rationale

The development of consensus guidelines for interpretation of Prostate-Specific Membrane Antigen (PSMA)-Positron Emission Tomography (PET) is needed to provide more consistent reports in clinical practice. The standardization of PSMA-PET interpretation may also contribute to increasing the data reproducibility within clinical trials. Finally, guidelines in PSMA-PET interpretation are needed to communicate the exact location of findings to referring physicians, to support clinician therapeutic management decisions.

Methods

A panel of worldwide experts in PSMA-PET was established. Panelists were selected based on their expertise and publication record in the diagnosis or treatment of PCa, in their involvement in clinical guidelines and according to their expertise in the clinical application of radiolabeled PSMA inhibitors. Panelists were actively involved in all stages of a modified, nonanonymous, Delphi consensus process.

Results

According to the findings obtained by modified Delphi consensus process, panelist recommendations were implemented in a structured report for PSMA-PET.

Conclusions

The E-PSMA standardized reporting guidelines, a document supported by the European Association of Nuclear Medicine (EANM), provide consensus statements among a panel of experts in PSMA-PET imaging, to develop a structured report for PSMA-PET in prostate cancer and to harmonize diagnostic interpretation criteria.

更新日期：2021-02-19

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