补充维生素C和E与运动引起的迟发性肌肉酸痛：系统评价,Antioxidants

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补充维生素C和E与运动引起的迟发性肌肉酸痛：系统评价
Antioxidants ( IF 6.0 ) Pub Date : 2021-02-12 , DOI: 10.3390/antiox10020279
María F. Torre , María Martinez-Ferran , Néstor Vallecillo , Sergio L. Jiménez , Carlos Romero-Morales , Helios Pareja-Galeano

运动引起的肌肉损伤可能会产生多种后果，例如延迟发作的肌肉酸痛，氧化应激过程中自由基释放的副作用。为了减轻氧化应激反应，一些研究小组已经评估了口服抗氧化剂的摄入量。这项审查检查补充维生素C和/或维生素E是否能够预防或减轻离心运动后延迟发作的肌肉酸痛。搜索PubMed，Web of Science，Medline和Embase数据库，以确定符合纳入标准的研究：主要的随机对照试验，年龄在16-80岁之间的健康男性和女性参与者，以及摄入维生素C和/或不含其他补品的维生素E，加上可控制的离心运动方案。进一步的要求是测量肌肉酸痛或延迟发作的肌肉酸痛的标志。本文考虑了2000年1月至2020年6月发布的所有英文原版或翻译成英文的全文文章。最终确定了14项研究，包括280名参与者，230名男性和50名16-30岁的女性。所有参与者都是健康的个体，其体育锻炼的起始水平不同。在两项研究中，补充剂是急性的，在十二项中是补充剂，其补充是由八项研究中的维生素C，两项研究中的维生素E以及两项研究中的两种组成。与安慰剂组相比，仅在14项研究中的3项中，在所有时间点，对维生素C和/或维生素E的补充引起的肌肉酸痛都明显减少。

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Supplementation with Vitamins C and E and Exercise-Induced Delayed-Onset Muscle Soreness: A Systematic Review

Muscle damage induced by exercise may have several consequences such as delayed-onset muscle soreness, a side-effect of the release of free radicals during oxidative stress. To mitigate the oxidative stress cascade, the oral intake of antioxidants has been assessed by several research groups. This review examines whether supplementation with vitamin C and/or vitamin E is able to prevent or attenuate delayed-onset muscle soreness after eccentric exercise. The PubMed, Web of Science, Medline, and Embase databases were searched to identify studies meeting the inclusion criteria: primary randomized control trials, healthy male and female participants aged 16–80 years, and an intervention consisting of the intake of vitamin C and/or vitamin E without other supplements plus a controlled eccentric exercise regimen. Further requirements were the measurement of muscle soreness or markers of delayed-onset muscle soreness. All original full-text articles in English or translated into English published from January 2000 to June 2020 were considered for this review. Fourteen studies were finally identified, including 280 participants, 230 men, and 50 women aged 16–30 years. All participants were healthy individuals with different starting levels of physical activity. Supplementation was acute in two studies and chronic in 12, and its consisted of vitamin C in eight studies, vitamin E in two studies, and both in four studies. Only in 3 of the 14 studies was muscle soreness found to be significantly reduced in response to vitamin C and/or vitamin E supplementation at all time points when compared to the placebo group. Despite some studies showing the beneficial effects of chronic supplementation with these vitamins on muscle soreness manifesting 24–72 hours after eccentric exercise, the evidence is so far insufficient to confirm that the intake of antioxidant vitamins is able to minimize delayed-onset muscle soreness in this context.

更新日期：2021-02-12

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