Abstract

An efficient method for the synthesis of 1-isopropyl-4-isothiocyanato-4-methylcyclohex-1-ene has been developed with p-menth-3-en-1-amine as raw material. Next, a number of p-menth-3-en-1-amine thiourea derivatives (4a–f) have been obtained from the reactions between 1-isopropyl-4-isothiocyanato-4-methylcyclohex-1-ene and cyclohexylamine or the reactions between p-menth-3-en-1-amine and different isothiocyanates. Then, the herbicidal activities of these compounds were evaluated. The result indicated that some of these newly synthesised compounds displayed remarkable herbicidal activities against annual ryegrass. In addition, the derivative containing cyclohexane ring (4a) displayed much higher herbicidal activity against annual ryegrass than the derivatives containing benzene ring.

摘要

以对薄荷-3-烯-1-胺为原料，开发了一种合成1-异丙基-4-异硫氰酸根-4-甲基环己-1-烯的有效方法。接下来，从 1-isopropyl-4-isothiocyanato-4-methylcyclohex-1-ene 和 cyclohexylamine 之间的反应或反应中获得了许多 p-menth-3-en-1-amine 硫脲衍生物 ( 4a – f ) p-menth-3-en-1-amine 和不同的异硫氰酸酯之间的关系。然后，评估这些化合物的除草活性。结果表明，其中一些新合成的化合物对一年生黑麦草表现出显着的除草活性。此外，含有环己烷环的衍生物（4a) 对一年生黑麦草的除草活性比含苯环的衍生物高得多。