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Synthesis of 2-(methoxymethyl)isoindolin-1-imine derivatives via an unusual Delépine reaction
Tetrahedron Letters ( IF 1.5 ) Pub Date : 2021-02-04 , DOI: 10.1016/j.tetlet.2021.152866 Igor V. Levkov , Andrii I. Kysil , Angelina V. Biitseva , Sergey V. Shilin , Nathalie Saffon-Merceron , Tatyana V. Yegorova , Zoia V. Voitenko
中文翻译:
通过不寻常的Delépine反应合成2-(甲氧基甲基)异吲哚啉-1-亚胺衍生物
更新日期:2021-03-04
Tetrahedron Letters ( IF 1.5 ) Pub Date : 2021-02-04 , DOI: 10.1016/j.tetlet.2021.152866 Igor V. Levkov , Andrii I. Kysil , Angelina V. Biitseva , Sergey V. Shilin , Nathalie Saffon-Merceron , Tatyana V. Yegorova , Zoia V. Voitenko
The synthesis of 2-(methoxymethyl)isoindolin-1-imine derivatives via an unusual Delépine reaction is reported. The substrate substituents’ influence on the reaction course was studied, and a possible reaction mechanism proposed. The structure of 2-(methoxymethyl)isoindolin-1-imine was confirmed by X-ray diffraction analysis.
中文翻译:
通过不寻常的Delépine反应合成2-(甲氧基甲基)异吲哚啉-1-亚胺衍生物
据报道,通过不寻常的Delépine反应合成2-(甲氧基甲基)异吲哚啉-1-亚胺衍生物。研究了底物取代基对反应过程的影响,并提出了可能的反应机理。通过X射线衍射分析确认了2-(甲氧基甲基)异吲哚啉-1-亚胺的结构。