A practical and mild synthesis of pentafluorophenoxy ketone in a continuous flow microfluidic reactor has been developed through 1,3-Dibromo-5,5-dimethylhydantoin (DBH)/DMSO mediated oxidative coupling of styrenes with pentafluorophenol. Moreover, a series of pentafluorophenoxy ketone products were provided in moderate to good yields under metal-free conditions. A magnifying continuous flow system was erected to verify the appliance of this method.

中文翻译：

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1,3-二溴-5,5-二甲基乙内酰脲（DBH）/ DMSO介导的苯乙烯氧化双官能化：五氟苯氧基酮的微流合成

通过1,3-二溴-5,5-二甲基乙内酰脲（DBH）/ DMSO介导的苯乙烯与五氟苯酚的氧化偶联，已经开发了在连续流微流反应器中实用，温和地合成五氟苯氧基酮的方法。此外，在无金属条件下以中等到良好的产率提供了一系列五氟苯氧基酮产品。建立了一个放大的连续流系统，以验证该方法的适用性。