Fitoterapia ( IF 2.5 ) Pub Date : 2021-02-03 , DOI: 10.1016/j.fitote.2021.104844 Zheng-Yi Qu 1 , Yu Zong 2 , Pei-He Zheng 1 , Yin-Ping Jin 1 , Wei Li 3 , He-Cheng Wang 2 , Ya-Li Li 1 , Ying-Ping Wang 3
Four new malonylginsenosides, malonylnotoginsenoside Fe (1), malonylnotoginsenoside Ra1 (2), malonylgypenoside LXXV (3), and malonylginsenoside Mc (4), together with two known analogues, malonylfloralginsenoside Rc1 (5) and malonylginsenoside Rc (6), were isolated from the fresh fruits of Panax notoginseng. Their structures were determined by MS and NMR experiments. The anti-proliferative activities of the malonylginsenosides (1–6) against SH-SY5Y human neuroblastoma cell line were evaluated using the MTT assay.
中文翻译:
三七鲜果中新的丙二酰人参皂苷
四个新malonylginsenosides,malonylnotoginsenoside的Fe(1),malonylnotoginsenoside太阳神1(2),malonylgypenoside LXXV(3),和malonylginsenoside MC(4),具有两个已知类似物一起,malonylfloralginsenoside RC 1(5)和malonylginsenoside RC(6),分别为从三七的新鲜果实中分离。它们的结构由MS和NMR实验确定。使用 MTT 测定评估丙二酸甘油酯 ( 1-6 ) 对 SH-SY5Y 人神经母细胞瘤细胞系的抗增殖活性。