Microbial pathogens attack every plant tissue, including leaves, roots, shoots, and flowers during all growth stages. Thus, they cause several diseases resulting in a plant's failure or loss of the whole crop in severe cases. To combat the pathogens attack, plants produce some biologically active toxic compounds known as saponins. The saponins are secondary metabolic compounds produced in healthy plants with potential anti-pathogenic activity and serve as potential chemical barriers against pathogens. Saponins are classified into two major groups the steroidal and terpenoid saponins. Here, we reported the significance of saponin toxins in the war against insect pests, fungal, and bacterial pathogens. Saponins are present in both cultivated (chilies, spinach, soybean, quinoa, onion, oat, tea, etc.) and wild plant species. As they are natural toxic constituents of plant defense, breeders and plant researchers aiming to boost plant imm

unity should focus on transferring these compounds in cash crops.

微生物病原体在所有生长阶段攻击每一个植物组织，包括叶、根、芽和花。因此，它们会引起多种疾病，严重时会导致植物歉收或整个作物损失。为了对抗病原体的攻击，植物会产生一些具有生物活性的有毒化合物，称为皂苷。皂苷是健康植物中产生的次生代谢化合物，具有潜在的抗病原体活性，可作为对抗病原体的潜在化学屏障。皂苷分为两大类：甾体皂苷和萜类皂苷。在这里，我们报道了皂苷毒素在对抗害虫、真菌和细菌病原体的战争中的重要性。皂苷存在于栽培植物（辣椒、菠菜、大豆、藜麦、洋葱、燕麦、茶等）和野生植物中。由于它们是植物防御的天然有毒成分，育种者和植物研究人员致力于提高植物防御能力

团结应集中精力将这些化合物转移到经济作物中。