Pore size distribution is crucial for the application of nanofiltration membrane in size-selective separation of industrial fluids. In this work, a novel combined interfacial polymerization (IP) and in-situ sol-gel strategy was proposed to fabricate composite nanofiltration membrane with narrow pore size distribution. Aqueous solution of piperazine and polyvinyl alcohol (PVA) was employed to perform interfacial polymerization with organic solution of trimesoyl chloride and tetraethyl orthosilicate (TEOS) on porous support. The non-reactive additive TEOS within the interfacially synthesized selective separation layer was then employed to perform sol-gel. The space-limited hydrolysis and condensation of TEOS molecules and their chemical bonding with PVA molecules were confirmed by analyzing membrane physico-chemical property and were found to be effective in tuning mean pore diameter, narrowing the pore size distribution and thus enhancing membrane perm-selectivity. Compared to those of membrane PA1 with similar mean pore size fabricated by only IP technique, the water permeability and rejection ratio of PEG1000 to raffinose (R_PEG1000/R_raffinose) of membrane PA-TEOS0.5 fabricated by combined IP and sol-gel technique were higher by 25.0 and 20.1%, respectively. Moreover, static adsorption and dynamic deposition tests using aqueous bovine serum albumin solution proved that in-situ sol-gel process could endow the membrane with better protein fouling resistance.

孔径分布对于纳米过滤膜在工业流体的尺寸选择分离中的应用至关重要。在这项工作中，提出了一种新颖的结合界面聚合（IP）和原位溶胶-凝胶策略的复合材料，以制备孔径分布窄的复合纳米过滤膜。使用哌嗪和聚乙烯醇（PVA）的水溶液与均苯三甲酰氯和原硅酸四乙酯（TEOS）的有机溶液在多孔载体上进行界面聚合。然后采用界面合成的选择性分离层中的非反应性添加剂TEOS进行溶胶凝胶。通过分析膜的理化性质，证实了TEOS分子在空间上的水解和缩合以及它们与PVA分子的化学键合，并发现它们可以有效地调节平均孔径，缩小孔径分布，从而提高膜的渗透选择性。 。与仅使用IP技术制备的具有相似平均孔径的PA1膜相比，PEG1000与棉子糖（R结合IP和溶胶-凝胶技术制备的膜PA-TEOS0.5的_PEG1000 / R_棉子糖）分别高25.0％和20.1％。此外，使用牛血清白蛋白水溶液进行的静态吸附和动态沉积测试证明，原位溶胶-凝胶工艺可以使膜具有更好的抗蛋白质结垢性。