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Graphene Liquid Cell Electron Microscopy: Progress, Applications, and Perspectives
ACS Nano ( IF 15.8 ) Pub Date : 2021-01-04 , DOI: 10.1021/acsnano.0c10229 Jungjae Park 1 , Kunmo Koo 1 , Namgyu Noh 1 , Joon Ha Chang 1 , Jun Young Cheong 1 , Kyun Seong Dae 1 , Ji Su Park 1 , Sanghyeon Ji 1 , Il-Doo Kim 1 , Jong Min Yuk 1
ACS Nano ( IF 15.8 ) Pub Date : 2021-01-04 , DOI: 10.1021/acsnano.0c10229 Jungjae Park 1 , Kunmo Koo 1 , Namgyu Noh 1 , Joon Ha Chang 1 , Jun Young Cheong 1 , Kyun Seong Dae 1 , Ji Su Park 1 , Sanghyeon Ji 1 , Il-Doo Kim 1 , Jong Min Yuk 1
Affiliation
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Graphene liquid cell electron microscopy (GLC-EM), a cutting-edge liquid-phase EM technique, has become a powerful tool to directly visualize wet biological samples and the microstructural dynamics of nanomaterials in liquids. GLC uses graphene sheets with a one carbon atom thickness as a viewing window and a liquid container. As a result, GLC facilitates atomic-scale observation while sustaining intact liquids inside an ultra-high-vacuum transmission electron microscopy chamber. Using GLC-EM, diverse scientific results have been recently reported in the material, colloidal, environmental, and life science fields. Here, the developments of GLC fabrications, such as first-generation veil-type cells, second-generation well-type cells, and third-generation liquid-flowing cells, are summarized. Moreover, recent GLC-EM studies on colloidal nanoparticles, battery electrodes, mineralization, and wet biological samples are also highlighted. Finally, the considerations and future opportunities associated with GLC-EM are discussed to offer broad understanding and insight on atomic-resolution imaging in liquid-state dynamics.
中文翻译：
石墨烯液体细胞电子显微镜：进展，应用和前景。
石墨烯液体细胞电子显微镜（GLC-EM）是一种先进的液相EM技术，已成为直接可视化湿生物样品和液体中纳米材料的微观结构动力学的强大工具。GLC使用具有一个碳原子厚度的石墨烯片作为观察窗和液体容器。结果，GLC促进了原子级观察，同时保持了超高真空透射电子显微镜室内的完整液体。使用GLC-EM，最近在材料，胶体，环境和生命科学领域报道了各种科学成果。在此，总结了诸如第一代面纱型电池，第二代井型电池和第三代液流电池等GLC制造技术的发展。此外，近期还对胶体纳米颗粒，电池电极，矿化和湿生物样品进行了GLC-EM研究。最后，讨论了与GLC-EM相关的考虑因素和未来机会，以提供对液态动力学中原子分辨率成像的广泛理解和见识。
更新日期：2021-01-26
中文翻译：
石墨烯液体细胞电子显微镜：进展，应用和前景。
石墨烯液体细胞电子显微镜（GLC-EM）是一种先进的液相EM技术，已成为直接可视化湿生物样品和液体中纳米材料的微观结构动力学的强大工具。GLC使用具有一个碳原子厚度的石墨烯片作为观察窗和液体容器。结果，GLC促进了原子级观察，同时保持了超高真空透射电子显微镜室内的完整液体。使用GLC-EM，最近在材料，胶体，环境和生命科学领域报道了各种科学成果。在此，总结了诸如第一代面纱型电池，第二代井型电池和第三代液流电池等GLC制造技术的发展。此外，近期还对胶体纳米颗粒，电池电极，矿化和湿生物样品进行了GLC-EM研究。最后，讨论了与GLC-EM相关的考虑因素和未来机会，以提供对液态动力学中原子分辨率成像的广泛理解和见识。
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