Taking a novel composite soft-template combining a cationic surfactant CTAB and trimellitic acid, the uniform hedgehog-like bismuth sulfide micro-nanostructures were successfully fabricated through a hydrothermal method, using Bi(NO₃)₃ as a bismuth source and thiourea as a sulfur source to slowly release S^2- ions. The as-synthesized hedgehog-like bismuth sulfide micro-nanostructures, taking the outer diameter size of about 4 μm, were assembled by Bi₂S₃ thin nanorods possessed nano-scale cross-section. The length of Bi₂S₃ thin nanorods is up to 2 μm and the tip diameter size is around 50 nm, compared to the larger root diameter. XRD characterization of the as-prepared hedgehog-like bismuth sulfide nanomaterial testified its quadrature-phase crystal. The effects of the concentrations of reactants and additives on the morphology and size of Bi₂S₃ particles were studied and the possible formation mechanism of the hedgehog-like Bi₂S₃ micro-nanostructures was explored. The resulting hedgehog-like bismuth sulfide sample was employed to manufacture immune sensor and the testing result indicated that micro-nanostructures could not only enhance reaction current by employing the electrode reduction of hydrogen peroxide thionine by a HRP catalysis, but also the catalytic current intensity was linearly proportional to the AFP concentration in the range of 0.01∼20 ng/mL, with a linear correlation coefficient of 0.9974 and a slope of 0.2878. It is worth mentioning that the proposed-manner can be applied to detect serum AFP antigen.

以一种新型的阳离子表面活性剂CTAB和偏苯三酸组合的软模板为模板，以Bi（NO ₃）₃为铋源，硫脲为硫磺，通过水热法成功制备了均匀的刺猬样硫化铋微纳米结构。源缓慢释放S ^2-离子。通过具有纳米级横截面的Bi ₂ S ₃细纳米棒组装合成的刺猬状硫化铋微纳米结构，其外径尺寸约为4μm 。Bi ₂ S ₃的长度与较大的根部直径相比，细的纳米棒可达2μm，尖端直径大小约为50 nm。制备的刺猬样硫化铋纳米材料的XRD表征证明了其正交相晶体。研究了反应物和添加剂的浓度对Bi ₂ S ₃颗粒的形态和尺寸的影响，以及刺猬状Bi ₂ S ₃的可能形成机理。探索了微纳米结构。用刺猬样的硫化铋样品制备免疫传感器，测试结果表明，微纳米结构不仅可以通过HRP催化过氧化氢硫氨酸的电极还原反应来增强反应电流，而且催化电流强度可以达到峰值。在0.01〜20 ng / mL范围内与AFP浓度呈线性比例关系，线性相关系数为0.9974，斜率为0.2878。值得一提的是，提出的方法可用于检测血清AFP抗原。