Clioquinol (CQ) is a mass-produced drug with broad-spectrum antifungal and antibacterial properties. This neurodegenerative medicine has attracted significant attention in the pharmaceutical field. However, excessive administration of CQ presents neurotoxic effects that require its early detection and effective countermeasures. Electrochemical detection can be beneficial in this regard, using functional material architectures with multiple advanced features. A unique emphasis is placed on manipulating these hierarchical structures, for advanced functions, offering an impressive perspective for monitoring systems. In this paper, we report on the innovative synthesis of distinct structures of AB₂O₄ (AB = Zn, Co, and Mn) spinel metal oxide anchored sulfur-doped reduced graphene oxide (S-rGO) for the effective detection of CQ. Fascinatingly, unique flower-like manganese cobaltite (MCO) exhibits superior structural advantages over other spinels, and doping of S-rGO into the framework marks a significant improvement in electrochemical properties. The highly symmetrical floral architecture with straight edges and facets provides defect-rich active sites, and the dissolution of S-rGO facilitates faster electron transfer and improved surface area. A wide linear response range, low detection limit, excellent reproducibility, and stability show that this material offers an efficient electrocatalyst that reinforces the practical viability of S-rGO doped MCO spinel for analysis and monitoring of real samples. The unique structural characteristics of the synthesized electrocatalyst can further extend its functions and applications, thereby expanding its potential capabilities.

中文翻译：

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包裹在硫掺杂的还原石墨烯氧化物上的类似三维的杂化AB ₂ O ₄（AB = Zn，Co和Mn）的表面工程：电催化剂在间苯二酚检测中的作用研究

Clioquinol（CQ）是具有广谱抗真菌和抗菌特性的量产药物。这种神经退行性药物在制药领域引起了极大的关注。但是，过量服用CQ具有神经毒性作用，需要早期发现并采取有效的对策。在这方面，使用具有多个高级功能的功能性材料体系结构，电化学检测可能是有益的。独特的重点是为高级功能操纵这些层次结构，为监视系统提供了令人印象深刻的视角。在本文中，我们报告了AB ₂ O ₄不同结构的创新合成（AB = Zn，Co和Mn）尖晶石金属氧化物锚定的硫掺杂还原氧化石墨烯（S-rGO），可有效检测CQ。令人着迷的是，独特的花状锰酸钴（MCO）具有优于其他尖晶石的结构优势，并且将S-rGO掺杂到骨架中标志着电化学性能的显着改善。具有笔直边缘和刻面的高度对称的花卉结构提供了缺陷丰富的活性位点，S-rGO的溶解促进了更快的电子转移并改善了表面积。宽的线性响应范围，低的检测限，出色的重现性和稳定性表明该材料提供了一种有效的电催化剂，可增强S-rGO掺杂的MCO尖晶石在实际样品分析和监测中的实用性。