Tetrahedron Letters ( IF 1.5 ) Pub Date : 2020-12-23 , DOI: 10.1016/j.tetlet.2020.152721 Augusto Rivera , Diego González-Salas , Jaime Ríos-Motta
In this work, a coupling reaction of aryl diazonium salts with a poly-N-nucleophile is developed for the synthesis of a variety of heterobicyclic tetrakis- and bistriazene compounds. The transformation proceeds smoothly in basic medium with good and moderate yields. In addition to the expected 3,3′-methanediylbis{1,5-bis[(E)-aryldiazenyl]-1,3,5-triazepanes}, two classes of heterobicyclic bis-triazenes were obtained by two ring rearrangement reactions. Using this method, an unknown class of organic compounds containing the saturated bis(imidazolidinyl)-methane unit can be accessed efficiently.
中文翻译:
杂双环四和双三氮烯的合成:3,3'-乙烷-1,2-二基双(1,3,5-三氮杂双环[3.2.1]辛烷)(ETABOC)与带有给电子基团的重氮盐之间的反应
在这项工作中,开发了芳基重氮盐与聚N-亲核试剂的偶联反应,用于合成各种杂双环四和双三氮烯化合物。转化在基本培养基中顺利进行,且产量中等。除了预期的3,3'- methanediylbis {1,5-双[(ë) - aryldiazenyl ] -1,3,5- triazepanes},杂双-三氮烯的两个类由两个环的重排反应得到。使用这种方法,可以有效地获得未知的含有饱和双(咪唑烷基)-甲烷单元的有机化合物。