Various bioactive aromatic compounds containing the indole nucleus showed clinical and biological applications. Indole scaffold has been found in many of the important synthetic drug molecules which gave a valuable idea for treatment and binds with high affinity to the multiple receptors helpful in developing new useful derivatives. Indole derivatives possess various biological activities, i.e., antiviral, anti-inflammatory, anticancer, anti-HIV, antioxidant, antimicrobial, antitubercular, antidiabetic, antimalarial, anticholinesterase activities, etc. which created interest among researchers to synthesize a variety of indole derivatives. From the literature, it is revealed that indole derivatives have diverse biological activities and also have an immeasurable potential to be explored for newer therapeutic possibilities.

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吲哚衍生物的生物潜力简要回顾

含有吲哚核的各种生物活性芳族化合物显示出临床和生物学应用。在许多重要的合成药物分子中都发现了吲哚支架，这给治疗提供了有价值的想法，并与多种受体高亲和力结合，有助于开发新的有用衍生物。吲哚衍生物具有多种生物活性，即抗病毒，抗炎，抗癌，抗HIV，抗氧化剂，抗微生物，抗结核，抗糖尿病，抗疟疾，抗胆碱酯酶活性等，这引起了研究人员对合成各种吲哚衍生物的兴趣。从文献中可以看出，吲哚衍生物具有多种生物活性，并且还具有不可估量的潜力，可用于新的治疗方法。