Alkylation of 7-amino-3-tert-butyl-4-oxo-4,6-dihydropyrazolo[5,1-c][1,2,4]triazine-8-carbonitrile led to N1-substituted derivative, which upon treatment with NaH and MeI in DMF was converted to 1-benzyl-3-tert-butyl-7-dimethylamino-4-oxo-1,4-dihydropyrazolo-[5,1-c][1,2,4]triazine-8-carbonitrile. The latter reacted with Grignard reagents to give high yields of new 3-tert-butyl-3-R-4-oxo-1,2,3,4-tetrahydropyrazolo[5,1-c][1,2,4]triazines (R = Alk, Ph). The reaction course and conditions were studied, and spectral characteristics of the products are discussed.

中文翻译：

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新型 4-oxo-1,2,3,4-四氢吡唑并[5,1-c][1,2,4]三嗪的合成

7-amino-3-tert-butyl-4-oxo-4,6-dihydropyrazolo[5,1-c][1,2,4]triazine-8-carbonitrile 的烷基化导致 N1-取代的衍生物，在处理后用 NaH 和 MeI 在 DMF 中转化为 1-benzyl-3-tert-butyl-7-dimethylamino-4-oxo-1,4-dihydropyrazolo-[5,1-c][1,2,4]triazine-8 -腈。后者与格氏试剂反应得到高产率的新 3-叔丁基-3-R-4-氧代-1,2,3,4-四氢吡唑并[5,1-c][1,2,4]三嗪(R = Alk, Ph)。研究了反应过程和条件，讨论了产物的光谱特性。