The present work focuses on astaxanthin (ASX) extraction from shrimp wastes using ultrasound-assisted extraction (UAE) natural deep eutectic solvents (NaDESs) and the utilization of ASX-rich DES extract (ASX-DES extract) for preparing biodegradable active packaging. The effect of hydrogen bond donor (HBD)/acceptor (HBA) molar ratio, ultrasound amplitude, and extraction time for the ASX extraction was observed, and influential parameters were optimized using three-level-factor Box-Behnken design (BBD) with response surface methodology (RSM). The ASX-NaDES extract obtained in the optimum condition (68.98 ± 1.22 μg/g of shrimp waste), which was predicted by the model (69.09 μg/g of waste), was further used as plasticizer for chitosan (CS)-based biodegradable films. Films prepared using the ASX-DES/CS extract show better radical scavenging activities than films prepared using pure NaDES/CS. Thermal stability and optimal and mechanical properties of the prepared films were also observed. ASX extraction using UAE NaDESs and further utilization of the ASX-DES extract in biodegradable films can play an important role in green chemistry.

目前的工作集中在使用超声波辅助提取（UAE）天然深共熔溶剂（NaDES）从虾废料中提取虾青素（ASX），以及利用富含ASX的DES提取物（ASX-DES提取物）来制备可生物降解的活性包装。观察了氢键供体（HBD）/受体（HBA）摩尔比，超声幅度和ASX提取时间的影响，并使用具有响应的三级因素Box-Behnken设计（BBD）优化了影响参数表面方法学（RSM）。由模型预测（69.09μg/ g废物）在最佳条件下（68.98±1.22μg/ g虾废物）获得的ASX-NaDES提取物进一步用作基于壳聚糖（CS）的可生物降解的增塑剂电影。与使用纯NaDES / CS制备的薄膜相比，使用ASX-DES / CS提取物制备的薄膜表现出更好的自由基清除活性。还观察到所制备膜的热稳定性以及最佳和机械性能。使用阿联酋NaDES进行ASX提取以及在可生物降解薄膜中进一步利用ASX-DES提取物可在绿色化学中发挥重要作用。