(S)-9-(2,3-Dihydroxypropyl)adenine, a novel nucleoside analog, the sugar moiety of which is replaced by an aliphatic chain, inhibits the replication in vitro of several DNA and RNA viruses, including vaccinia, herpes simplex (types 1 and 2), measles, and vesicular stomatitis. It is also effective in vivo in reducing the mortality rate of mice inoculated intranasally with vesicular stomatitis virus.

中文翻译：

---

(S)-9-(2,3-二羟丙基)腺嘌呤：一种具有广谱抗病毒活性的脂肪族核苷类似物

(S)-9-(2,3-二羟丙基)腺嘌呤是一种新型核苷类似物，其糖部分被脂肪链取代，可抑制多种 DNA 和 RNA 病毒的体外复制，包括牛痘、单纯疱疹病毒。 1 型和 2 型）、麻疹和水泡性口炎。它还在体内有效降低鼻内接种水疱性口炎病毒的小鼠的死亡率。