Palladium-Catalyzed Intermolecular Polarity-Mismatched Addition of Unactivated Alkyl Radicals to Unactivated Alkenes,ACS Catalysis

当前位置： X-MOL 学术 › ACS Catal. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Palladium-Catalyzed Intermolecular Polarity-Mismatched Addition of Unactivated Alkyl Radicals to Unactivated Alkenes
ACS Catalysis ( IF 11.3 ) Pub Date : 2020-11-18 , DOI: 10.1021/acscatal.0c04013
Xiaojin Wu ₁ , Guanlin Xiao _{1,

2} , Yalan Ding ₁ , Ying Zhan ₁ , Yao Zhao ₁ , Rizhi Chen ₃ , Teck-Peng Loh ₄

Affiliation

A palladium-catalyzed intermolecular polarity-mismatched addition of unactivated alkyl radicals to unactivated alkenes was developed for the first time. In the two-component dicarbofunctionalization, a variety of primary, secondary, and tertiary unactivated alkyl halides regioselectively reacted with various unactivated olefins. A series of structurally complex heteropolycycles decorated with a quaternary carbon center have been efficiently synthesized.

中文翻译：