Interaction of quinoxalin-2(1H)-one-3-carbaldoximes with 1,2-benzenediamine derivatives in AcOH or n-BuOH at reflux in the presence of sulfuric acid as catalyst was found to give 3-(benzimidazol-2-yl)quinoxalin-2(1H)-ones and 2-(benzimidazol-2-yl)quinoxalines in relatively good yields, which formed as a result of the Weidenhagen reaction and Mamedov rearrangement, respectively. The reaction in AcOH afforded 2-(benzimidazol-2-yl)quinoxalines in preference to the 3-(benzimidazol-2-yl)quinoxalin-2(1H)-ones, while the reverse result was obtained in n-BuOH. The synthetic utility of this strategy was illustrated by the concise, one-pot synthesis of 3-(3H-imidazo[4,5-b]pyridin-2-yl)quinoxalin-2(1H)-ones.

在硫酸为催化剂的条件下，回流下喹喔啉-2（1 H）-一-3-羰醛肟与1,2-苯二胺衍生物在AcOH或n- BuOH中的相互作用，得到3-（苯并咪唑-2-基）喹喔啉-2（1 H）-酮和2-（苯并咪唑-2-基）喹喔啉的收率相对较高，这分别是由于Weidenhagen反应和Mamedov重排而形成的。在AcOH中的反应提供的2-（苯并咪唑-2-基）喹喔啉优先于3-（苯并咪唑-2-基）喹喔啉-2（1 H）-酮，而在n- BuOH中得到相反的结果。简明的一锅合成3-（3 H-咪唑并[4,5- b] pyridin-2-yl）quinoxalin-2（1 H）-ones。