Pancreatic cancer is a rapidly progressing disease with a poor prognosis. We still have many questions about the pathogenesis, early diagnosis and precise treatment of this disease. Organoids, a rapidly emerging technology, can simulate the characteristics of pancreatic tumors. Using the organoid model of pancreatic cancer, we can study and explore the characteristics of pancreatic cancer, thereby effectively guiding clinical practice and improving patient prognosis. This review introduces the development of organoids, comparisons of organoids with other preclinical models and the status of organoids in basic research and clinical applications for pancreatic cancer.

胰腺癌是一种进展迅速的疾病，预后较差。关于该疾病的发病机理，早期诊断和精确治疗，我们仍然有许多问题。类器官，是一种迅速出现的技术，可以模拟胰腺肿瘤的特征。使用胰腺癌的类器官模型，我们可以研究和探索胰腺癌的特征，从而有效地指导临床实践并改善患者的预后。这篇综述介绍了类器官的发展，类器官与其他临床前模型的比较以及类器官在胰腺癌基础研究和临床应用中的地位。