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Development of Mass Sensitive Sensor Platform Based on Plasma Polymerization Technique: Quartz Tuning Fork as Transducer
Applied Surface Science ( IF 6.3 ) Pub Date : 2021-02-01 , DOI: 10.1016/j.apsusc.2020.148360 Gizem Kaleli-Can , Hatice Ferda Özgüzar , Mehmet Mutlu
Applied Surface Science ( IF 6.3 ) Pub Date : 2021-02-01 , DOI: 10.1016/j.apsusc.2020.148360 Gizem Kaleli-Can , Hatice Ferda Özgüzar , Mehmet Mutlu
Abstract This paper describes a modification process of QTFs’ prongs with stable amine containing bilayer plasma polymer film and an application of quartz tuning fork (QTF) as a transducer for biomedical application. To produce stable amine containing film, first, we created plasma polymer films from hexane precursors. We then subjected those films to a second capping layer of ethylenediamine plasma polymer. The film was characterized by contact angle measurement, atomic force microscopy, and X-ray photoelectron spectroscopy. The effect of the interfacial structure onto stability was also analyzed in air. A model protein, BSA, sensing experiments were examined by measuring the shift in the resonance frequency of QTFs. The performance of the proposed sensor was investigated in terms of quality factor. These findings reveal that amine containing bilayer coated QTFs have the potential to be used in mass sensitive biosensor applications for future.
中文翻译:
基于等离子体聚合技术的质量敏感传感器平台的开发:石英音叉作为换能器
摘要 本文描述了一种用稳定的含胺双层等离子体聚合物膜对 QTF 尖头进行改性的过程,以及石英音叉 (QTF) 作为传感器在生物医学应用中的应用。为了生产稳定的含胺薄膜,首先,我们用己烷前体制造了等离子体聚合物薄膜。然后我们将这些薄膜置于乙二胺等离子体聚合物的第二个覆盖层上。通过接触角测量、原子力显微镜和 X 射线光电子能谱对该薄膜进行表征。还在空气中分析了界面结构对稳定性的影响。通过测量 QTF 共振频率的变化来检查模型蛋白 BSA 传感实验。所提出的传感器的性能在品质因数方面进行了研究。
更新日期:2021-02-01
中文翻译:
基于等离子体聚合技术的质量敏感传感器平台的开发:石英音叉作为换能器
摘要 本文描述了一种用稳定的含胺双层等离子体聚合物膜对 QTF 尖头进行改性的过程,以及石英音叉 (QTF) 作为传感器在生物医学应用中的应用。为了生产稳定的含胺薄膜,首先,我们用己烷前体制造了等离子体聚合物薄膜。然后我们将这些薄膜置于乙二胺等离子体聚合物的第二个覆盖层上。通过接触角测量、原子力显微镜和 X 射线光电子能谱对该薄膜进行表征。还在空气中分析了界面结构对稳定性的影响。通过测量 QTF 共振频率的变化来检查模型蛋白 BSA 传感实验。所提出的传感器的性能在品质因数方面进行了研究。