Dealing with the Foreign‐Body Response to Implanted Biomaterials: Strategies and Applications of New Materials,Advanced Functional Materials

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Dealing with the Foreign‐Body Response to Implanted Biomaterials: Strategies and Applications of New Materials
Advanced Functional Materials ( IF 18.5 ) Pub Date : 2020-10-23 , DOI: 10.1002/adfm.202007226
Donghui Zhang ₁ , Qi Chen ₂ , Chao Shi ₂ , Minzhang Chen ₂ , Kaiqian Ma ₂ , Jianglin Wan ₂ , Runhui Liu _{1,

2}

Affiliation

Foreign‐body response caused by implanted biomaterials seriously impedes the function of implants and is a major obstacle to the development of implantable biomaterials and medical devices. Recent advances in implantable biomaterials and medical devices have provided strategies to resist the foreign‐body response. In this review, the mechanism of the foreign‐body response and conventional strategies to mitigate foreign‐body response is briefly introduced. Then, three types of promising foreign‐body response resisting materials are focused and the advantages, characteristics, and applications of each material are discussed. Finally, prospects are put forward for future development of foreign‐body response resisting materials and current challenges that require in‐depth study.

中文翻译：

处理异物对植入生物材料的反应：新材料的策略和应用

植入的生物材料引起的异物反应严重阻碍了植入物的功能，并且是植入式生物材料和医疗设备发展的主要障碍。植入式生物材料和医疗设备的最新进展为抵抗异物反应提供了策略。在这篇综述中，简要介绍了异物反应的机制和减轻异物反应的常规策略。然后，重点讨论了三种有希望的抗异物响应材料，并讨论了每种材料的优点，特性和应用。最后，展望了抗异物响应材料的未来发展以及需要深入研究的当前挑战。

更新日期：2020-10-23

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