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Wound Healing: Carbon Dots Induce Epithelial‐Mesenchymal Transition for Promoting Cutaneous Wound Healing via Activation of TGF‐β/p38/Snail Pathway (Adv. Funct. Mater. 43/2020)
Advanced Functional Materials ( IF 18.5 ) Pub Date : 2020-10-23 , DOI: 10.1002/adfm.202070283 Zilin Wang 1, 2 , Lili Liu 1, 2 , Wenhuan Bu 3 , Mengdan Zheng 1, 2 , Nianqiang Jin 3 , Kai Zhang 4 , Xiaowei Xu 1, 2 , Ding Zhou 5 , Bai Yang 4 , Hongchen Sun 1
Advanced Functional Materials ( IF 18.5 ) Pub Date : 2020-10-23 , DOI: 10.1002/adfm.202070283 Zilin Wang 1, 2 , Lili Liu 1, 2 , Wenhuan Bu 3 , Mengdan Zheng 1, 2 , Nianqiang Jin 3 , Kai Zhang 4 , Xiaowei Xu 1, 2 , Ding Zhou 5 , Bai Yang 4 , Hongchen Sun 1
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In article number 2004886, Xiaowei Xu, Ding Zhou, Hongchen Sun, and co‐workers synthesize carbon dots with excellent biocompatibility via microwave‐assisted heating of ascorbic acid and polyethyleneimine. The synthesized carbon dots can induce the epithelial‐mesenchymal transition process by activating the transforming growth factor‐β/p‐38 mitogen‐activated kinase/Snail signaling pathway, leading to increased cell motility, and thus promote full‐thickness cutaneous wound healing with fewer scars.
中文翻译：
伤口愈合：碳点通过激活TGF-β/ p38 / Snail途径诱导上皮-间质转化，促进皮肤伤口愈合（Adv。Funct。Mater。43/2020）
在编号2004886的文章中，徐晓伟，周鼎，孙宏晨和他的同事通过抗坏血酸和聚乙烯亚胺的微波辅助加热合成了具有优异生物相容性的碳点。合成的碳点可通过激活转化生长因子-β/ p-38丝裂原激活的激酶/ Snail信号通路来诱导上皮-间质转化过程，从而导致细胞运动性增强，从而促进全层皮肤伤口愈合，而所需的时间更少疤痕。
更新日期：2020-10-25
中文翻译：
伤口愈合：碳点通过激活TGF-β/ p38 / Snail途径诱导上皮-间质转化，促进皮肤伤口愈合（Adv。Funct。Mater。43/2020）
在编号2004886的文章中，徐晓伟，周鼎，孙宏晨和他的同事通过抗坏血酸和聚乙烯亚胺的微波辅助加热合成了具有优异生物相容性的碳点。合成的碳点可通过激活转化生长因子-β/ p-38丝裂原激活的激酶/ Snail信号通路来诱导上皮-间质转化过程，从而导致细胞运动性增强，从而促进全层皮肤伤口愈合，而所需的时间更少疤痕。
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