Amide-tethered aryloxazoline motifs are important structural moiety because of ubiquity in medicinal chemistry, functional materials and pincer ligands. In recent years, much attention about N-(2-(4,5-dihydrooxazol-2-yl)phenyl)amides has been focused on ortho C−H functionalization of amides. Herein a highly efficient rhodium(III) catalyzed oxidative olefination of N-(2-(4,5-dihydrooxazol-2-yl)phenyl)amides with arylethenes via extraordinary N-aryl C-H bond functionalization was developed.

中文翻译：

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铑催化的N-（2-（4,5-二氢恶唑-2-基）苯基）酰胺与丙烯酰胺的非常规N-芳基CH键官能化

由于在医学化学，功能材料和钳位配体中无处不在，因此，由酰胺束缚的芳基恶唑啉基序是重要的结构部分。近年来，对N-（2-（4,5-二氢恶唑-2-基）苯基）酰胺的关注已集中在酰胺的邻位CH官能化上。本文开发了N-（2-（4,5-二氢恶唑-2-基）苯基）酰胺与芳烃经非凡的N-芳基CH键官能化反应的高效铑（III）催化氧化烯化反应。