We propose a bacteria-dye combination screening strategy for the fluorescence staining of a specific bacteria strain. The threat of bacteria and its drug-resistance is getting ever more severe, and they are constantly harming human beings. Under these circumstances, precise identification of a specific bacteria is essential for diagnosing and finding the proper drugs for treatment. In this study, we discovered that a positively-charged diamine-containing BMeS-p-A dye has a selective staining ability of Gram-negative Acinetobacter baumannii (AB) and carbapenem-resistant AB (CRAB) over other bacteria strains. We systematically analyzed the photophysical properties, sensing abilities, and the antibiotic effect of BMeS-p-A. We utilized the BMeS-p-A for monitoring the biofilm of AB and CRAB in medical supplies; urethral tract catheters. The results of this study will facilitate further applications in a variety of medical fields.

我们提出了一种细菌-染料组合筛选策略，用于特定细菌菌株的荧光染色。细菌的威胁及其耐药性变得越来越严重，它们不断伤害着人类。在这种情况下，对特定细菌的精确识别对于诊断和寻找合适的治疗药物至关重要。在这项研究中，我们发现带正电荷的含二胺的BMeS-pA染料具有对革兰氏阴性鲍曼不动杆菌的选择性染色能力。（AB）和抗碳青霉烯的AB（CRAB）优于其他细菌菌株。我们系统地分析了BMeS-pA的光物理性质，传感能力和抗生素作用。我们利用BMeS-pA监测医疗用品中AB和CRAB的生物膜；尿道导管。这项研究的结果将促进在各种医学领域的进一步应用。