Synthesis of biomimetic adhesive for achieving robust interface bonding attracts numerous attentions for various applications. Inspired by the metal ions-assisted coacervation mechanism of sandcastle worm glue, novel copolymer/Mⁿ⁺ complex wet adhesives are synthesized successfully, containing hydrophobic component, bidentate anionic component and temperature sensitive component. The anionic segments in copolymer interacts with different metal ions (Ca²⁺/Mg²⁺/Cu²⁺) in solution through coacervation reaction along with temperature-strengthened dehydration effect, resulting in the formation of biomimetic adhesives. The wet adhesion strength of the biomimetic adhesives is tunable based on the ions species, concentrations and coordination time, while the adhesion mechanisms are analyzed and discussed in details. The biomimetic adhesives not only can be used to tightly bond two solid surfaces underwater, but also is robust and effective in air. For example, current adhesives can firmly bonding various substrates including glass, Si, PTFE and animal bone. More importantly, the biomimetic adhesives are capable of sealing leaky pipes or vessels in harsh wet environment. Due to no dopamine chemistry, current adhesives involve no oxidation problem. We firmly believe this new system would demonstrate promising applications in surface engineering, wet sealing/repairing and tissue engineering.

用于实现牢固的界面粘合的仿生粘合剂的合成引起了各种应用的广泛关注。在沙堡蠕虫胶的金属离子辅助凝聚机理的启发下，成功地合成了新型共聚物/ Mn ⁺复合湿胶，其中含有疏水成分，双齿阴离子成分和温度敏感成分。共聚物中的阴离子链段与不同的金属离子（Ca ²⁺ / Mg ²⁺ / Cu ²⁺）在溶液中通过凝聚反应以及温度强化的脱水作用，导致仿生粘合剂的形成。仿生粘合剂的湿粘合强度可根据离子种类，浓度和配位时间进行调节，同时对粘合机理进行了详细分析和讨论。仿生胶粘剂不仅可以用来在水下牢固地粘合两个固体表面，而且在空气中也很坚固有效。例如，当前的粘合剂可以牢固地粘合包括玻璃，Si，PTFE和动物骨头的各种基材。更重要的是，仿生粘合剂能够在恶劣的潮湿环境中密封泄漏的管道或容器。由于没有多巴胺化学性质，目前的粘合剂不涉及氧化问题。