Choline chloride based deep eutectic solvents have showed great potential in lignocellulosic biomass pretreatment. In this study, for DES pretreatment with different hydrogen bond donners of different raw materials under different reaction conditions, multivariate analysis methods including principal component analysis and partial least squares analysis were used for reveal the pretreatment mechanism by evaluating the inner relationships among 42 key process factors. Furthermore, based on molecular simulation, the detailed relationships between key variables were further analyzed. Meanwhile, four-dimensional color graphs were used to intuitively reveal the synergistic influence of multivariate conditions variables on pretreatment effect to obtain better economic benefits and energy consumption indicators for DES pretreatment. The results showed that HBD hydrophilic ability, HBD polarity, HBD acidity, HBD ability to form hydrogen bonds, molar ratio of HBD to choline chloride and pretreatment severity had great influence on the Choline chloride based deep eutectic solvents pretreatment effect.

基于氯化胆碱的深共熔溶剂在木质纤维素生物质预处理中显示出巨大潜力。在这项研究中，对于在不同反应条件下使用不同原料的不同氢键供体的DES预处理，通过评估42个关键工艺因素之间的内在联系，采用了包括主成分分析和偏最小二乘分析在内的多元分析方法来揭示预处理机理。 。此外，基于分子模拟，进一步分析了关键变量之间的详细关系。同时，利用二维彩色图直观地揭示了多元条件变量对预处理效果的协同影响，以获得更好的经济效益和DES预处理的能耗指标。