Abstract In order to find new CAA fungicides, twenty four new threoninamide carbamate derivatives were synthesized. The reaction was optimized. Their structures were confirmed by 1H NMR, 13C NMR, single crystal and HRFTMS. Fungicidal activities were evaluated against P. capsici and P. cubensi. All of them exhibited excellent activity against Phytophthora capsici in vitro with EC50 values of 0.53 to 20.17 μg/mL. Notably, compounds 3-11, 3-19 and 3-20 possessed good control effect(>70%) against P. capsici in vivo at 6.25 μg/mL.

中文翻译：

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一些新型苏氨酰胺氨基甲酸酯衍生物的合成、结构及杀菌活性

摘要 为了寻找新的CAA杀菌剂，合成了24个新的苏氨酰胺氨基甲酸酯衍生物。反应得到优化。它们的结构经 1H NMR、13C NMR、单晶和 HRFTMS 证实。针对 P. capsici 和 P.cubensi 评估了杀真菌活性。它们都在体外对辣椒疫霉表现出优异的活性，EC50 值为 0.53 至 20.17 μg/mL。值得注意的是，化合物 3-11、3-19 和 3-20 在 6.25 μg/mL 时具有良好的体内控制效果（>70%）对抗辣椒疟原虫。