Asymmetric catalytic hydrogenations of imines and enamines with chiral transition-metal complexes bearing chiral ligands are among the most green and powerful approaches for the elaboration of chiral amine structures in organic synthesis. This review focuses on recent applications of asymmetric hydrogenations of imine and enamine substrates in the total syntheses of natural products. These applications include diverse processes involving asymmetric transfer hydrogenation (ATH) and asymmetric hydrogenation (AH) to form key chiral amine motifs in natural products with good efficiency and high-level enantiocontrol.

中文翻译：

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天然产物合成中亚胺和烯胺的不对称催化加氢

亚胺和烯胺与带有手性配体的手性过渡金属配合物的不对称催化氢化是有机合成中手性胺结构的最绿色和最有效的方法之一。这篇综述集中在亚胺和烯胺底物的不对称氢化在天然产物的总合成中的最新应用。这些应用包括涉及不对称转移氢化（ATH）和不对称氢化（AH）的各种过程，这些过程以良好的效率和高水平对映体控制在天然产物中形成关键的手性胺基序。