Antibiotics and multi-drug resistant bacteria are present extensively in different environmental matrices, and considered as contaminants of emerging concern. This study evaluated the feasibility and effectiveness of using electrooxidation (EO) with Magnéli phase Ti₄O₇ anode to simultaneously remove bacterial pathogens, antibiotics and antibacterial resistance genes (ARGs) from water. A model pathogen, multidrug-resistant Salmonella enterica serotype Typhimurium DT104, was completely deactivated with 6.2 log reduction in 15 min at the current density of 10.0 mA cm⁻², while ARGs (i.e., TetG, floR and sul1), class 1 integron gene (intI1) and virulence genes (invA and spvC) that were contained in the pathogen were removed by as much as 99.65 % to 99.94%. Model antibiotics, tetracycline (TC) and sulfadimethoxine (SDM), were degraded over 93% in the same EO treatment system within 3 h. It was found that both direct electron transfer (DET) and ^•OH-mediated oxidation played important roles in the removal of the ARGs during the EO process. EO may be a promising tool to control the spread of antibiotic resistence by removing pathogens, antibiotics and ARGs simultaneously.

抗生素和耐多种细菌的细菌广泛存在于不同的环境基质中，被认为是引起人们关注的污染物。这项研究评估了使用Magnéli相Ti ₄ O ₇阳极电氧化（EO）同时从水中去除细菌病原体，抗生素和抗菌素耐药基因（ARG）的可行性和有效性。在10.0 mA cm ^-2的电流密度下，模型病原体多药耐药肠炎沙门氏菌鼠伤寒沙门氏菌DT104型在15分钟内以6.2 log减少量完全失活，而ARGs（即TetG，floR和sul1）是1类整合子基因（intI1）去除了病原体中包含的毒力基因（invA和spvC）高达99.65％至99.94％。在同一EO处理系统中，模型抗生素四环素（TC）和磺胺二甲氧嘧啶（SDM）在3小时内降解了93％以上。结果发现，直接电子转移（DET）和^• OH介导的氧化过程中的EO过程中去除ARG游戏中发挥了重要作用。EO可能是通过同时去除病原体，抗生素和ARGs来控制抗生素耐药性扩散的有前途的工具。