Background: Benzimidazoles and its derivatives have been attracting interest for many years because of their biological activities. Benzimidazoles containing different heterocyclic moieties have wide range of biological activities such as antimicrobial, antioxidant, anticancer, antiviral, etc.

Methods: In this study, some benzimidazole derivatives containing furan, oxadiazole, triazole and thiadiazole moieties have been synthesized and then evaluated for their antioxidant and antiurease activities.

Results: The results showed that all the tested benzimidazoles indicated remarkable urease inhibitory potentials with IC50 values ranging between 0.303±0.03 to 0.591±0.08 µM.

Conclusion: In conclusion, synthesized benzimidazole derivatives showed good antioxidant and antiurease activities. Heterocyclic groups on benzimidazole nucleus enhance the activities.

背景：苯并咪唑及其衍生物由于其生物活性而引起人们的兴趣多年。含有不同杂环部分的苯并咪唑具有广泛的生物学活性，例如抗微生物剂，抗氧化剂，抗癌剂，抗病毒剂等。

方法：本研究合成了一些含呋喃，恶二唑，三唑和噻二唑部分的苯并咪唑衍生物，然后评估其抗氧化和抗脲酶活性。

结果：结果表明，所有测试的苯并咪唑均显示出显着的脲酶抑制潜能，IC50值为0.303±0.03至0.591±0.08 µM。

结论：总之，合成的苯并咪唑衍生物具有良好的抗氧化和抗脲酶活性。苯并咪唑核上的杂环基团可增强活性。