Kaempferol-3-O-α-L-rhamanopyranosyl-(1'''-6'')-β-D-glucopyranoside (1) (Nicotiflorin or kaempferol-3-O-rutinoside), isolated from the aerial parts of Osyris wightiana Wall. ex Wight, exhibited a potent antiglycation activity in vitro. A short and efficient route to kaempferol-3-O-rutinoside (1) is also described in this paper. To study the structure-activity relationship, few other derivatives of kaempferol were also evaluated for their antiglycation activity. Moreover the cytotoxicity analysis was also performed for these compounds. The Structure-Activity Relationship (SAR) studies showed that sugar derivatives of kaempferol possess a promising antiglycation activity.

Kaempferol-3-O-α-L-rhamanopyranosyl-（1'''-6''）-β-D-glucopyranoside（1）（Nicotiflorin or kaempferol-3-O-rutinoside），从Osyris的空中部分分离怀特安娜墙。ex Wight在体外表现出有效的抗糖化活性。本文还描述了一种短而有效的方法来制备山奈酚3-O-芸香糖苷（1）。为了研究结构-活性关系，山emp酚的其他衍生物几乎没有被评估其抗糖化活性。此外，还对这些化合物进行了细胞毒性分析。结构-活性关系（SAR）研究表明，山emp酚的糖衍生物具有良好的抗糖化活性。