Purpose: To review the indications and clinical profile of neonatal admissions at King Abdullah University Hospital in Jordan.
Materials and Methods: We conducted a cross-sectional review of all neonates admitted to the neonatal intensive care unit between September 2016 and September 2018. Collected data include demographic characteristics, indications for admission, morbidities and mortality, and discharge outcomes. Findings were reported among term and preterm infants.
Results: A total of 1444 infants were admitted during the study period of whom 1332 (92.2%) were inborn and 612 (42.4%) were term neonates. Of the 832 preterm infants, 545 were late preterm (34– 36 6/7 gestation) and 125 had very low birth weight (˂ 1500 grams); 925 (64%) were born by cesarean section. Respiratory failure of the newborn (41.2%) and prematurity (33.3%) were the main indications for admission among the whole cohort. Maternal prolonged premature rupture of membranes (PROM) was observed in nearly half the admissions of term infants. Hypoxic ischemic encephalopathy (3.2% vs 0.7%, p 0.01) and congenital anomalies (5% vs 1.2%, p 0.03) were more common in term infants. The rate of bronchopulmonary dysplasia was 39% among < 28-week and 28% among < 32-week premature infants. Sepsis was encountered in 59 infants. The overall mortality rate was 3.8%. Prematurity was the main predisposing factor for mortality (Adjusted OR: 9.9, 95% CI: 3.5, 27.6).
Conclusion: The majority of neonatal admissions at our institution are term and late preterm infants delivered by cesarean section. Prematurity, respiratory failure of the newborn, and suspected sepsis due to maternal PROM are the leading causes of admission. The mortality rate is within WHO target to achieve Sustainable Development Goal 3. Population-based studies are needed to make better conclusions that represent the whole Jordanian population. A revisit for the indications of cesarean deliveries may help to improve the neonatal outcomes.

Keywords: neonatal outcomes, Jordan, NICU admissions, neonatal mortality


中文翻译：

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新生儿入院的适应症和临床概况：约旦单个学术中心的横断面描述性分析

目的：回顾约旦阿卜杜拉国王大学医院新生儿入院的适应症和临床概况。
材料和方法：我们对 2016 年 9 月至 2018 年 9 月期间入住新生儿重症监护病房的所有新生儿进行了横断面审查。收集的数据包括人口特征、入院指征、发病率和死亡率以及出院结果。研究结果是在足月儿和早产儿中报告的。
结果：研究期间共入院婴儿1444例，其中出生儿1332例（92.2%），足月儿612例（42.4%）。在 832 名早产儿中，545 名是晚期早产儿（妊娠 34-36 6/7），125 名出生体重极低（1500 克）；925 名 (64%) 是通过剖腹产出生的。新生儿（41.2%）和早产儿（33.3%）呼吸衰竭是整个队列入院的主要指征。近一半的足月儿入院时观察到母亲出现长时间胎膜早破（PROM）。缺氧缺血性脑病（3.2% vs 0.7%，p < 0.01）和先天性异常（5% vs 1.2%，p < 0.03）在足月儿中更为常见。28周以下的早产儿中支气管肺发育不良的发生率为39%，32周以下的早产儿中支气管肺发育不良的发生率为28%。59 名婴儿患有败血症。总死亡率为3.8%。早产是死亡的主要诱发因素（调整后 OR：9.9，95% CI：3.5，27.6）。
结论：我们机构入院的新生儿大部分是剖宫产的足月儿和晚期早产儿。早产、新生儿呼吸衰竭以及产妇胎膜早破导致的疑似败血症是入院的主要原因。死亡率处于世卫组织实现可持续发展目标 3 的目标范围内。需要进行基于人群的研究，以得出代表整个约旦人口的更好结论。重新审视剖腹产的指征可能有助于改善新生儿结局。

关键词：新生儿结局、约旦、新生儿重症监护病房入院率、新生儿死亡率